COA & Testing
Independent third-party lab reports for the batches shown below. Only results the laboratory reported for that batch are shown. Look up any vial code or browse all products at batch reports.
Research Summary: The following information is provided for research context only.
Semaglutide Research Overview
Semaglutide is a GLP-1 receptor agonist analogue with an extended half-life relative to native GLP-1, achieved through fatty acid modification that enables albumin binding and resistance to DPP-4 enzymatic degradation. It is one of the most widely characterized reference compounds in in-vitro incretin and receptor-signaling research.
Mechanism of Action
Semaglutide binds to GLP-1 receptors expressed in pancreatic beta-cell, hypothalamic, and gastrointestinal tissue models. Receptor activation drives glucose-dependent insulinotropic signaling and downstream cAMP pathway activity. Its prolonged half-life makes it a useful reference compound for studying sustained GLP-1 receptor engagement in preclinical in-vitro models.
Research Applications
Semaglutide is commonly used as a reference compound in in-vitro GLP-1 receptor-binding assays, comparative incretin agonist studies, and receptor-signaling characterization alongside Tirzepatide and Retatrutide.
Compound Specifications
Lyophilized Semaglutide 10mg at high purity, independently third-party tested. Molecular weight: 4113.6 Da. Batch SEM010-001. Each RR vial has a QR code linking to its batch’s independent COA (also in the COA & Testing tab and at /verify). No paper COA ships with orders.
Storage and Handling
Store at -20°C prior to reconstitution. Reconstitute with sterile bacteriostatic water. Once in solution, store at 4°C and use within 28 days.
For research use only. Not for human or veterinary use.
Structure, CAS and molecular data, mechanism, storage and published literature: see our Semaglutide research reference.
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